Did you know that all mammals have a biochemical communication system within them that plays a critical role in the regulation of their physiological systems and their everyday experience? That biochemical communication system is called the Endocannabinoid System, or ECS for short, and its goal is to bring about homeostasis, or healthy balance, within our bodies.
The Endocannabinoid System is a group of endogenous cannabinoid receptors located in the brains as well as the central and peripheral nervous systems of all mammals, including dogs and cats! There are two primary endocannabinoid receptors that have been identified. CB1 receptors are located primarily in the brain and nervous system, while CB2 receptors are predominantly found in peripheral organs and tissues as well as the immune system.
Those receptors respond pharmacologically to chemical compounds found in marijuana and medicinal hemp called cannabinoids. One of the ways that this process is described is by using the “key and lock” metaphor. Our bodies, as well as the bodies of all mammals, have specific binding sites (“locks”) on the surface of many types of cells, and our bodies produce several endocannabinoids (“keys”) that bind to those CB receptors to “unlock” them. In short, cannabinoids, especially THC, CBN, and CBD, actually activate and interact with those CB receptors, and when those receptors are stimulated, a variety of physiological processes occur which actually change the way our bodies function!
from the article "The Endocannabinoid System," from The Canna Dog Treat Company webpage.
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